Acetazolamide 250mg

Generic For: Diamox

Acetazolamide 250mg (brand name Diamox) is a carbonic anhydrase inhibitor used to treat glaucoma, prevent and reduce symptoms of altitude sickness, and manage certain types of edema and seizures. After a licensed provider reviews your information and confirms a prescription is appropriate, your order ships from a licensed U.S. pharmacy.

Select Quantity *

50-day supply · $0.40/tablet

How It Works

  1. Select your medication
  2. Licensed providers review & prescribe
  3. Our licensed U.S. pharmacists fill your prescription
  4. Delivered to you as soon as the next day

Price: $40.00

HSA/FSA Eligible
Get Started

*Doctor visit fee & delivery cost not included in price. Refills at provider discretion.

Pharmacist Support Fast Shipping Licensed U.S. Pharmacy

Buy Acetazolamide 250mg (Diamox) Online

A carbonic anhydrase inhibitor for glaucoma, altitude sickness, and edema

Acetazolamide 250mg Quick Facts

Drug classCarbonic anhydrase inhibitor
TreatsGlaucoma, altitude sickness, edema, certain seizures
FormTablet
Typical dosingTake 1-2 tablets by mouth twice daily, starting 1-2 days before travel and continuing daily. Continue for up to 3 more days after travel.
Prescription requiredYes — prescription only

What Is Acetazolamide 250mg?

Acetazolamide is a prescription medication in the carbonic anhydrase inhibitor class, sold under the brand name Diamox. It works by blocking the enzyme carbonic anhydrase, which lowers fluid pressure in the eye, promotes fluid loss through the kidneys, and helps the body adjust to high altitudes. Doctors prescribe acetazolamide for glaucoma, prevention and treatment of acute mountain sickness, edema caused by heart failure or medications, and certain seizure disorders. It is taken by mouth as a 250mg tablet, with dosing tailored to the condition being treated.

What Does Acetazolamide 250mg Treat?

Chronic open-angle glaucoma
Secondary glaucoma
Acute angle-closure glaucoma (preoperative, short-term)
Acute mountain sickness (altitude sickness) prevention and treatment
Edema due to congestive heart failure
Drug-induced edema
Centrencephalic epilepsies (adjunctive)

Acetazolamide 250mg Dosage

Glaucoma: 250 mg by mouth 1 to 4 times daily.
Altitude sickness: 500 mg to 1,000 mg daily in divided doses, starting 24 to 48 hours before ascent and continuing for 48 hours at altitude or as needed.
Edema: 250 mg to 375 mg by mouth once daily in the morning.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Acetazolamide 250mg Side Effects

Common side effects

  • Tingling or numbness in fingers, toes, or face (paresthesia)
  • Altered taste, especially with carbonated drinks
  • Increased urination
  • Drowsiness or fatigue
  • Nausea or loss of appetite
  • Dizziness
  • Ringing in the ears (tinnitus)

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis)
  • Blood disorders (aplastic anemia, agranulocytosis)
  • Metabolic acidosis or severe electrolyte imbalance
  • Kidney stones or blood in urine
  • Liver problems (jaundice, dark urine)
  • Severe allergic reaction (rash, swelling, difficulty breathing)

Warnings & Interactions

Do not use if allergic to sulfonamides (sulfa drugs)
Contraindicated in significant liver disease or cirrhosis
Contraindicated in severe kidney disease and certain electrolyte imbalances (low sodium or potassium)
Avoid concurrent high-dose aspirin — risk of serious toxicity
May increase blood levels of other drugs (e.g., phenytoin, lithium interactions possible)
Long-term use in chronic angle-closure glaucoma is not recommended
May cause drowsiness — use caution when driving until you know how it affects you

Tell your prescriber about all medications, supplements, and health conditions before starting acetazolamide 250mg.

Talk to U.S.-Based Support

Our licensed pharmacy team in Boca Raton, Florida — real people, no overseas call centers.

Frequently Asked Questions

What is acetazolamide used for?

Acetazolamide is FDA-approved to treat glaucoma, prevent and reduce symptoms of acute mountain sickness (altitude sickness), manage edema from congestive heart failure or medications, and as add-on therapy for certain seizures. Your provider will determine whether it is appropriate for your condition.

Is acetazolamide the same as Diamox?

Yes. Diamox is the brand name for acetazolamide. The 250mg tablet contains the same active ingredient and is held to the same FDA standards as the brand product.

Do I need a prescription for acetazolamide?

Yes, acetazolamide is a prescription-only medication in the United States. A licensed provider must review your health information and issue a valid prescription before we can dispense it.

How does ordering and shipping work?

After you place your order, a licensed provider reviews your information to confirm the medication is appropriate. Once approved, your prescription is filled and shipped from a licensed U.S. pharmacy directly to your address.

When should I start acetazolamide for altitude sickness?

Per FDA labeling, dosing typically begins 24 to 48 hours before ascent and continues for 48 hours at high altitude, or longer if needed to control symptoms. Follow your provider's specific instructions, and descend if severe symptoms develop despite treatment.

What are the most common side effects of acetazolamide?

Common side effects include tingling in the fingers, toes, or face, changes in taste, increased urination, drowsiness, and mild nausea. Contact your provider if side effects are persistent, bothersome, or severe.

Can I take acetazolamide if I'm allergic to sulfa drugs?

Acetazolamide is a sulfonamide, so people with a sulfa allergy may be at risk of a serious reaction and should generally avoid it. Tell your provider about any drug allergies before starting this medication.