Prochlorperazine 10mg

Generic For: Compazine

Prochlorperazine 10mg (brand name Compazine) is a prescription phenothiazine medication used to control severe nausea and vomiting, and to treat schizophrenia. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.

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A phenothiazine anti-nausea medication for severe nausea, vomiting, and schizophrenia

Prochlorperazine 10mg Quick Facts

Drug classPhenothiazine antiemetic and antipsychotic
TreatsSevere nausea and vomiting, schizophrenia, short-term anxiety
FormTablet
Typical dosingTake 1 tablet by mouth every 6 hours as needed for nausea.
Prescription requiredYes — prescription only

What Is Prochlorperazine 10mg?

Prochlorperazine is a prescription medication in the phenothiazine class, sold under the brand name Compazine. It works by blocking dopamine receptors in the brain, which helps control severe nausea and vomiting. It is also FDA-approved to treat schizophrenia and, for short periods, non-psychotic anxiety. Prochlorperazine 10mg tablets are taken by mouth and require a prescription from a licensed provider.

What Does Prochlorperazine 10mg Treat?

Severe nausea
Severe vomiting
Schizophrenia
Short-term treatment of non-psychotic anxiety

Prochlorperazine 10mg Dosage

Severe nausea/vomiting: 5–10 mg by mouth 3–4 times daily.
Schizophrenia: 5–10 mg by mouth 3–4 times daily; adjusted gradually as directed.
Non-psychotic anxiety: 5 mg by mouth 3–4 times daily; do not exceed 20 mg/day or 12 weeks.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Prochlorperazine 10mg Side Effects

Common side effects

  • Drowsiness
  • Dizziness
  • Blurred vision
  • Dry mouth
  • Constipation
  • Restlessness
  • Skin reactions or rash
  • Low blood pressure

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Tardive dyskinesia (involuntary movements)
  • Neuroleptic malignant syndrome (high fever, muscle rigidity)
  • Seizures
  • Severe extrapyramidal reactions (muscle spasms, tremor)
  • Jaundice or signs of liver problems
  • Blood disorders (fever, sore throat, unusual bruising)

Warnings & Interactions

Boxed warning: increased mortality in elderly patients with dementia-related psychosis; not approved for this use
Do not use in children under 2 years or under 20 lbs
Do not use in comatose states or with large amounts of CNS depressants (alcohol, opioids, sedatives)
May cause tardive dyskinesia, which can be irreversible
May impair mental or physical abilities; use caution driving or operating machinery
Use caution in patients with glaucoma, seizure history, or heart disease
Tell your provider if pregnant or breastfeeding

Tell your prescriber about all medications, supplements, and health conditions before starting prochlorperazine 10mg.

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Frequently Asked Questions

What is prochlorperazine used for?

Prochlorperazine is FDA-approved to control severe nausea and vomiting and to treat schizophrenia. It may also be used short-term for non-psychotic anxiety when other treatments are not appropriate.

Do I need a prescription for prochlorperazine?

Yes. Prochlorperazine is a prescription-only medication in the U.S. A licensed provider must evaluate you and issue a valid prescription before a pharmacy can dispense it.

How does ordering and shipping work?

After you submit your prescription or complete a provider review, a licensed pharmacist verifies your order. Once approved, your medication ships from a licensed U.S. pharmacy directly to your address.

How quickly does prochlorperazine work for nausea?

Oral tablets typically begin working within 30 to 60 minutes, though response varies by individual. Follow your provider's dosing instructions and do not take more than prescribed.

Can I drink alcohol while taking prochlorperazine?

No, alcohol should be avoided. Combining prochlorperazine with alcohol or other CNS depressants can increase drowsiness, dizziness, and the risk of serious side effects.

Is prochlorperazine the same as Compazine?

Yes. Compazine is the original brand name for prochlorperazine. Generic prochlorperazine tablets contain the same active ingredient and are held to the same FDA standards.

What should I do if I miss a dose?

Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not double up on doses; contact your pharmacist if you are unsure.