Compazine 5mg

Generic For: Compazine

Compazine (prochlorperazine) 5mg is a prescription phenothiazine tablet used to control severe nausea and vomiting, and to treat schizophrenia and short-term non-psychotic anxiety. After a licensed provider reviews your information and prescription, your order ships from a licensed U.S. pharmacy.

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Compazine (prochlorperazine) is a phenothiazine medication used for severe nausea and vomiting, schizophrenia, and short-term anxiety.

Compazine 5mg Quick Facts

Drug classPhenothiazine antiemetic/antipsychotic
TreatsSevere nausea and vomiting, schizophrenia, short-term anxiety
FormTablet
Typical dosingTake 1 tablet by mouth every 6 hours as needed for nausea.
Prescription requiredYes — prescription only

What Is Compazine 5mg?

Compazine is the brand name for prochlorperazine, a first-generation phenothiazine medication. It works by blocking dopamine receptors in the brain, which helps calm the vomiting center and reduce psychotic symptoms. Compazine is most often prescribed to control severe nausea and vomiting, and it is also FDA-approved for schizophrenia and short-term treatment of non-psychotic anxiety. It is available as a 5mg oral tablet and requires a valid prescription.

What Does Compazine 5mg Treat?

Control of severe nausea and vomiting
Treatment of schizophrenia
Short-term treatment of generalized non-psychotic anxiety

Compazine 5mg Dosage

Severe nausea/vomiting: 5–10 mg by mouth 3–4 times daily.
Schizophrenia: 5–10 mg by mouth 3–4 times daily; adjust per response.
Non-psychotic anxiety: 5 mg by mouth 3–4 times daily; max 20 mg/day, not to exceed 12 weeks.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Compazine 5mg Side Effects

Common side effects

  • Drowsiness
  • Dizziness
  • Blurred vision
  • Dry mouth
  • Constipation
  • Restlessness (akathisia)
  • Skin reactions or sensitivity to sunlight
  • Low blood pressure on standing

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Tardive dyskinesia (involuntary movements, may be irreversible)
  • Neuroleptic malignant syndrome (high fever, rigidity, confusion)
  • Severe extrapyramidal symptoms (muscle spasms, tremor)
  • Signs of blood disorders (fever, sore throat, unusual bruising)
  • Jaundice or signs of liver problems
  • Seizures

Warnings & Interactions

Boxed warning: increased risk of death in elderly patients with dementia-related psychosis; not approved for this use
Do not use in comatose states or with large amounts of CNS depressants (alcohol, opioids, barbiturates)
Do not use in children under 2 years or under 20 lbs, or in pediatric surgery
May cause tardive dyskinesia; risk increases with duration of treatment
May impair alertness; avoid driving until you know how it affects you
Use caution with anticholinergic drugs, antihypertensives, and other dopamine antagonists
Tell your provider if you are pregnant, breastfeeding, or have glaucoma, seizures, or liver disease

Tell your prescriber about all medications, supplements, and health conditions before starting compazine 5mg.

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Frequently Asked Questions

What is Compazine used for?

Compazine (prochlorperazine) is FDA-approved to control severe nausea and vomiting, to treat schizophrenia, and for short-term treatment of non-psychotic anxiety. Your provider will determine whether it is appropriate for your condition.

Do I need a prescription for Compazine?

Yes. Compazine is a prescription-only medication in the U.S. A licensed healthcare provider must review your health information and issue or verify a valid prescription before it can be dispensed.

How does ordering and shipping work?

After you place an order, a licensed provider reviews your prescription and medical details. Once approved, your medication is dispensed and shipped from a licensed U.S. pharmacy in discreet packaging.

How quickly does Compazine work for nausea?

Oral prochlorperazine typically begins working within 30 to 60 minutes, though individual response varies. Follow your provider's dosing instructions and do not take more than prescribed.

Can I drink alcohol while taking Compazine?

No. Alcohol can increase drowsiness and other central nervous system effects of Compazine and should be avoided during treatment. Ask your pharmacist about interactions with your other medications.

What are the most common side effects of Compazine?

Common side effects include drowsiness, dizziness, blurred vision, dry mouth, and constipation. Contact your provider promptly if you notice involuntary movements, high fever, muscle stiffness, or other serious symptoms.

Is Compazine safe for older adults?

Compazine carries a boxed warning: elderly patients with dementia-related psychosis treated with antipsychotics have an increased risk of death, and it is not approved for that use. Older adults should use it only under close medical supervision.