Chlorthalidone 50mg

Generic For: Hygroton

Chlorthalidone (brand name Hygroton) is a thiazide-like diuretic, sometimes called a water pill, used to treat high blood pressure and fluid retention (edema) caused by heart failure, kidney disease, or liver disease. It works by helping the kidneys remove excess salt and water from the body. Order chlorthalidone 50mg tablets from our licensed U.S. pharmacy after a valid prescription review by a licensed provider.

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Buy Chlorthalidone 50mg Online

A thiazide-like diuretic for high blood pressure and fluid retention (edema)

Chlorthalidone 50mg Quick Facts

Drug classThiazide-like diuretic
TreatsHigh blood pressure, edema, fluid retention from heart failure
FormTablet
Typical dosingTake 1 tablet by mouth daily.
Prescription requiredYes — prescription only

What Is Chlorthalidone 50mg?

Chlorthalidone is a prescription thiazide-like diuretic, commonly known as a water pill. It lowers blood pressure and reduces swelling by helping the kidneys flush extra salt and water out of the body through urine. Chlorthalidone is used alone or with other medications to treat hypertension, and it also treats edema associated with heart failure, kidney disorders, and liver cirrhosis. It is available as a generic tablet and under the brand name Hygroton.

What Does Chlorthalidone 50mg Treat?

High blood pressure (hypertension)
Edema associated with congestive heart failure
Edema associated with liver cirrhosis
Edema associated with kidney disease, including nephrotic syndrome
Fluid retention caused by corticosteroid or estrogen therapy

Chlorthalidone 50mg Dosage

Hypertension: 25 mg by mouth once daily; may increase to 50 mg once daily if needed.
Edema: 50–100 mg by mouth once daily, or 100 mg every other day.
Take in the morning with food.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Chlorthalidone 50mg Side Effects

Common side effects

  • Dizziness or lightheadedness
  • Increased urination
  • Headache
  • Upset stomach or nausea
  • Loss of appetite
  • Muscle cramps
  • Constipation or diarrhea

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Signs of low potassium or electrolyte imbalance (irregular heartbeat, severe muscle weakness, confusion)
  • Severe dizziness or fainting
  • Allergic reaction (rash, hives, swelling, trouble breathing)
  • Eye pain or sudden vision changes (acute angle-closure glaucoma)
  • Severe dehydration (extreme thirst, very dry mouth, little or no urination)
  • Unusual bleeding or bruising

Warnings & Interactions

Do not use if allergic to chlorthalidone or other sulfonamide-derived drugs
Contraindicated in anuria (inability to urinate)
Can cause low potassium, sodium, and magnesium; periodic lab monitoring is recommended
May increase blood sugar and uric acid; use caution with diabetes or gout
Use caution with lithium — diuretics can raise lithium levels
May increase sensitivity to sunlight; use sun protection
Tell your provider if pregnant or breastfeeding before use

Tell your prescriber about all medications, supplements, and health conditions before starting chlorthalidone 50mg.

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Frequently Asked Questions

What is chlorthalidone used for?

Chlorthalidone is a thiazide-like diuretic used to treat high blood pressure and fluid retention (edema) caused by heart failure, kidney disease, or liver cirrhosis. It helps the kidneys remove excess salt and water from the body.

Do I need a prescription for chlorthalidone?

Yes. Chlorthalidone is a prescription-only medication in the United States. A licensed healthcare provider must review your health information and issue a valid prescription before we can dispense it.

How does ordering and shipping work?

Place your order online and provide your prescription, or have your provider send it directly to our pharmacy. After a licensed pharmacist verifies the prescription, your medication ships from our licensed U.S. pharmacy in discreet packaging.

Is chlorthalidone the same as hydrochlorothiazide?

No. Both are diuretics used for blood pressure, but chlorthalidone is a thiazide-like diuretic with a longer duration of action. Your provider will determine which medication is appropriate for you.

What time of day should I take chlorthalidone?

It is usually taken once daily in the morning with food to reduce nighttime urination. Follow the specific directions on your prescription label and ask your pharmacist if you have questions.

What should I avoid while taking chlorthalidone?

Avoid becoming dehydrated, limit alcohol, and use sun protection since the drug may increase sun sensitivity. Tell your provider about all medications you take, especially lithium, NSAIDs, and other blood pressure drugs.