Spironolactone 100mg
Generic For: Aldactone
Spironolactone (brand name Aldactone) is a potassium-sparing diuretic used to treat heart failure, high blood pressure, and fluid retention caused by liver or kidney conditions. After a licensed provider reviews your prescription, your spironolactone 100mg tablets ship directly from our licensed U.S. pharmacy.
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100-day supply · $0.45/tablet
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Buy Spironolactone 100mg Online
A potassium-sparing diuretic for heart failure, high blood pressure, and fluid retention (edema)
Spironolactone 100mg Quick Facts
| Drug class | Potassium-sparing diuretic (aldosterone antagonist) |
|---|---|
| Treats | Heart failure, high blood pressure, edema, primary hyperaldosteronism |
| Form | Tablet |
| Typical dosing | Take 1 Tablet by mouth daily. |
| Prescription required | Yes — prescription only |
What Is Spironolactone 100mg?
Spironolactone is a prescription medication known as a potassium-sparing diuretic, or "water pill." It works by blocking aldosterone, a hormone that causes the body to retain salt and water. This helps the body remove excess fluid while keeping potassium levels from dropping. Spironolactone is sold under the brand name Aldactone and is available as a 100mg tablet.
What Does Spironolactone 100mg Treat?
Heart failure (NYHA class III–IV with reduced ejection fraction)
High blood pressure (hypertension)
Edema from cirrhosis of the liver
Edema from nephrotic syndrome
Primary hyperaldosteronism
Hypokalemia (low potassium) in certain patients
Spironolactone 100mg Dosage
Heart failure: 25 mg by mouth once daily; may increase to 50 mg once daily as tolerated.
Hypertension: 25–100 mg by mouth daily, in single or divided doses.
Edema (cirrhosis/nephrotic syndrome): 100 mg by mouth daily (range 25–200 mg), in single or divided doses.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Spironolactone 100mg Side Effects
Common side effects
- Increased urination
- Dizziness or lightheadedness
- Breast tenderness or enlargement (gynecomastia)
- Nausea or vomiting
- Diarrhea
- Headache
- Irregular menstrual periods
- Drowsiness
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- High potassium levels (hyperkalemia) — irregular heartbeat, muscle weakness
- Severe allergic reaction (rash, swelling, difficulty breathing)
- Signs of dehydration or electrolyte imbalance (extreme thirst, confusion)
- Severe skin reactions (Stevens-Johnson syndrome, TEN)
- Kidney problems (decreased urination, swelling)
- Fainting or severe dizziness
Warnings & Interactions
Do not use with significant hyperkalemia or Addison's disease
Avoid potassium supplements and salt substitutes containing potassium unless directed
Use caution with ACE inhibitors, ARBs, and other potassium-sparing drugs — risk of hyperkalemia
NSAIDs may reduce effectiveness and increase potassium levels
Use caution in kidney impairment; monitor potassium and kidney function regularly
May cause gynecomastia; usually reversible after stopping
Tell your provider if pregnant or breastfeeding before use
Tell your prescriber about all medications, supplements, and health conditions before starting spironolactone 100mg.
Sources & References
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