Isosorbide Dinitrate 20mg
Generic For: Isordil
Isosorbide dinitrate 20mg (brand name Isordil) is a nitrate vasodilator tablet used to prevent angina (chest pain) in people with coronary artery disease. It works by relaxing blood vessels so the heart's workload and oxygen demand are reduced. Available with a valid prescription and shipped from a licensed U.S. pharmacy after review by a licensed provider.
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Buy Isosorbide Dinitrate 20mg (Isordil) Online
A nitrate vasodilator used to prevent angina (chest pain) caused by coronary artery disease
Isosorbide Dinitrate 20mg Quick Facts
| Drug class | Nitrate vasodilator |
|---|---|
| Treats | Angina prevention, coronary artery disease-related chest pain |
| Form | Tablet |
| Typical dosing | Take as directed by your physician by mouth. |
| Prescription required | Yes — prescription only |
What Is Isosorbide Dinitrate 20mg?
Isosorbide dinitrate is a prescription nitrate medication sold under the brand name Isordil. It is used to prevent episodes of angina, the chest pain that occurs when the heart muscle does not get enough oxygen due to coronary artery disease. The tablet relaxes and widens blood vessels, which lowers the heart's workload and improves blood flow. Because its onset is not fast enough, it is not intended to stop an angina attack that has already started.
What Does Isosorbide Dinitrate 20mg Treat?
Prevention of angina pectoris due to coronary artery disease
Chronic stable angina (long-term prevention)
Reducing frequency of angina episodes
Adjunct in heart failure regimens (as directed by a provider)
Isosorbide Dinitrate 20mg Dosage
Angina prevention: 5–40 mg by mouth 2–3 times daily; usual maintenance 10–40 mg per dose
Allow a daily nitrate-free interval of at least 14 hours to limit tolerance
Take exactly as prescribed; do not use to treat an acute angina attack
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Isosorbide Dinitrate 20mg Side Effects
Common side effects
- Headache
- Dizziness
- Lightheadedness
- Flushing
- Nausea
- Low blood pressure on standing
- Weakness or fatigue
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Severe hypotension (fainting, severe dizziness)
- Worsening angina or chest pain
- Fast, slow, or irregular heartbeat
- Signs of allergic reaction (rash, swelling, trouble breathing)
- Blurred vision or dry mouth (may signal overdose)
Warnings & Interactions
Do not use with PDE-5 inhibitors (sildenafil, tadalafil, vardenafil) or riociguat — risk of severe hypotension
Contraindicated with known hypersensitivity to nitrates
May cause severe low blood pressure, especially when standing or with alcohol
Tolerance can develop; a daily nitrate-free interval is needed
Use caution in volume depletion or existing low blood pressure
Do not stop abruptly without provider guidance; abrupt withdrawal may worsen angina
Not for relief of an acute angina attack
Tell your prescriber about all medications, supplements, and health conditions before starting isosorbide dinitrate 20mg.
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