Spironolactone 25mg
Generic For: Aldactone
Spironolactone 25mg (brand name Aldactone) is a potassium-sparing diuretic prescribed for heart failure, high blood pressure, fluid retention caused by liver or kidney conditions, and primary hyperaldosteronism. It works by blocking the hormone aldosterone, helping the body remove excess fluid while retaining potassium. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.
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Buy Spironolactone 25mg Online (Aldactone)
A potassium-sparing diuretic for heart failure, high blood pressure, and fluid retention (edema)
Spironolactone 25mg Quick Facts
| Drug class | Potassium-sparing diuretic (aldosterone antagonist) |
|---|---|
| Treats | Heart failure, high blood pressure, edema, primary hyperaldosteronism |
| Form | Tablet |
| Typical dosing | Take 1 Tablet by mouth daily. |
| Prescription required | Yes — prescription only |
What Is Spironolactone 25mg?
Spironolactone is a prescription medication in the potassium-sparing diuretic class, also known as an aldosterone antagonist. It blocks aldosterone, a hormone that causes the body to hold on to sodium and water, which helps reduce fluid buildup and lower blood pressure. Unlike many other diuretics, spironolactone helps the body retain potassium rather than lose it. The 25mg tablet is a commonly prescribed starting strength, sold under the brand name Aldactone.
What Does Spironolactone 25mg Treat?
Heart failure (NYHA class III–IV with reduced ejection fraction)
High blood pressure (hypertension)
Edema associated with liver cirrhosis
Edema associated with nephrotic syndrome
Primary hyperaldosteronism
Hypokalemia in patients on other diuretics
Spironolactone 25mg Dosage
Heart failure: 25 mg by mouth once daily; may increase to 50 mg once daily as directed.
Hypertension: 25–100 mg by mouth daily in single or divided doses.
Edema: 100 mg by mouth daily (range 25–200 mg), in single or divided doses.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Spironolactone 25mg Side Effects
Common side effects
- Dizziness or lightheadedness
- Drowsiness
- Nausea or vomiting
- Diarrhea
- Breast tenderness or enlargement (gynecomastia)
- Irregular menstrual periods
- Headache
- Leg cramps
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- High blood potassium (hyperkalemia) — muscle weakness, irregular heartbeat
- Severe dizziness or fainting
- Signs of kidney problems (decreased urination, swelling)
- Severe skin reactions (rash, blistering, peeling)
- Signs of electrolyte imbalance (confusion, extreme thirst, severe fatigue)
Warnings & Interactions
Do not use with significant kidney impairment or anuria
Do not use if you have high blood potassium (hyperkalemia) or Addison's disease
Avoid potassium supplements and potassium-rich salt substitutes unless directed
Use caution with ACE inhibitors, ARBs, and other potassium-sparing drugs (hyperkalemia risk)
NSAIDs may reduce effectiveness and increase kidney risk
May cause harm during pregnancy — discuss with your provider
Requires periodic monitoring of potassium and kidney function
Tell your prescriber about all medications, supplements, and health conditions before starting spironolactone 25mg.
Sources & References
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