Doxycycline Monohydrate 100mg
Generic For: Monodox
Doxycycline monohydrate 100mg (brand name Monodox) is a tetracycline-class antibiotic capsule used to treat a wide range of bacterial infections, including acne, respiratory tract infections, and certain sexually transmitted infections. It works by stopping the growth of susceptible bacteria. After review of your information by a licensed provider, your prescription ships from a licensed U.S. pharmacy.
Compare all Doxycycline options →
Select Quantity *
30-day supply · $0.58/capsule
How It Works
- Select your medication
- Licensed providers review & prescribe
- Our licensed U.S. pharmacists fill your prescription
- Delivered to you as soon as the next day
Price: $35.00
HSA/FSA Eligible*Doctor visit fee & delivery cost not included in price. Refills at provider discretion.
Buy Doxycycline Monohydrate 100mg Online (Monodox)
A tetracycline antibiotic for bacterial infections including acne, respiratory infections, and chlamydia
Doxycycline Monohydrate 100mg Quick Facts
| Drug class | Tetracycline antibiotic |
|---|---|
| Treats | Bacterial infections, acne, respiratory infections, chlamydia |
| Form | Capsule |
| Typical dosing | Take 2 capsules by mouth daily |
| Prescription required | Yes — prescription only |
What Is Doxycycline Monohydrate 100mg?
Doxycycline monohydrate is the monohydrate salt form of doxycycline, a broad-spectrum tetracycline antibiotic. It is prescribed for many bacterial infections, including respiratory tract infections, skin infections, severe acne, certain sexually transmitted infections, and tick-borne illnesses such as Rocky Mountain spotted fever. It can also be used to prevent malaria in travelers. Doxycycline monohydrate 100mg capsules are the generic equivalent of the brand Monodox and require a prescription in the United States.
What Does Doxycycline Monohydrate 100mg Treat?
Respiratory tract infections (e.g., community-acquired pneumonia)
Severe acne (adjunctive therapy)
Chlamydia and other sexually transmitted infections
Skin and soft tissue infections
Rickettsial infections (e.g., Rocky Mountain spotted fever)
Urinary tract infections caused by susceptible bacteria
Malaria prophylaxis
Doxycycline Monohydrate 100mg Dosage
100 mg by mouth every 12 hours on day 1, then 100 mg once daily
Severe infections: 100 mg by mouth every 12 hours
Duration per prescriber; take with a full glass of water
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Doxycycline Monohydrate 100mg Side Effects
Common side effects
- Nausea
- Vomiting
- Diarrhea
- Loss of appetite
- Sun sensitivity (photosensitivity)
- Skin rash
- Headache
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Severe or persistent diarrhea (possible C. difficile infection)
- Severe allergic reaction (swelling, difficulty breathing, hives)
- Esophageal irritation or ulceration (painful swallowing, chest pain)
- Severe skin reactions (blistering, peeling)
- Increased pressure in the skull (severe headache, vision changes)
- Signs of liver problems (yellowing of skin or eyes, dark urine)
Warnings & Interactions
Do not use if allergic to doxycycline or other tetracyclines
Avoid during pregnancy and in children under 8 (tooth discoloration, bone effects)
May reduce effectiveness of hormonal birth control; use backup contraception
Avoid prolonged sun exposure; use sunscreen
Separate from antacids, calcium, iron, and dairy by 2-3 hours
Take with plenty of water and remain upright to avoid esophageal irritation
May interact with warfarin, penicillins, and isotretinoin
Tell your prescriber about all medications, supplements, and health conditions before starting doxycycline monohydrate 100mg.
Sources & References
Talk to U.S.-Based Support
Our licensed pharmacy team in Boca Raton, Florida — real people, no overseas call centers.


