Erythromycin Topical Solution 2%

Generic For: Erygel

Erythromycin topical solution 2% is a prescription macrolide antibiotic applied to the skin to treat acne vulgaris. It works by reducing acne-causing bacteria on the skin and helping calm inflammatory breakouts. After a licensed provider reviews your information, your order ships from a licensed U.S. pharmacy.

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30-day supply · $0.83/mL

How It Works

  1. Select your medication
  2. Licensed providers review & prescribe
  3. Our licensed U.S. pharmacists fill your prescription
  4. Delivered to you as soon as the next day

Price: $50.00

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*Doctor visit fee & delivery cost not included in price. Refills at provider discretion.

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Buy Erythromycin Topical Solution 2% (Erygel) Online

A topical macrolide antibiotic for acne vulgaris and acne-related breakouts

Erythromycin Topical Solution 2% Quick Facts

Drug classTopical macrolide antibiotic
TreatsAcne vulgaris, inflammatory acne lesions
FormSolution
Typical dosingWash the affected area gently, then pat the skin completely dry. Apply a thin layer to the affected areas once or twice daily
Prescription requiredYes — prescription only

What Is Erythromycin Topical Solution 2%?

Erythromycin topical is a solution form of the antibiotic erythromycin that is applied directly to the skin. It is FDA-approved to treat acne vulgaris, the common form of acne that causes pimples, whiteheads, and blackheads. The medication works by slowing the growth of Cutibacterium acnes, the bacteria involved in inflammatory acne. It is available by prescription only and is typically applied to affected areas twice daily.

What Does Erythromycin Topical Solution 2% Treat?

Acne vulgaris
Inflammatory acne lesions (papules and pustules)
Mild to moderate facial acne
Acne on the chest, back, or shoulders (as directed by a provider)

Erythromycin Topical Solution 2% Dosage

Apply a thin layer to affected area(s) topically twice daily (morning and evening).
Cleanse and dry skin before applying.
Continue as directed; improvement may take several weeks.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Erythromycin Topical Solution 2% Side Effects

Common side effects

  • Dryness
  • Peeling or flaking skin
  • Burning or stinging on application
  • Itching
  • Redness (erythema)
  • Oily skin
  • Skin irritation

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Severe skin irritation or blistering
  • Signs of allergic reaction (rash, swelling, difficulty breathing)
  • Severe or persistent diarrhea (possible C. difficile-associated colitis)
  • Worsening acne or skin infection

Warnings & Interactions

For external use only; avoid eyes, nose, mouth, and mucous membranes
Do not use if allergic to erythromycin or any ingredient in the solution
Contains alcohol; may cause burning and is flammable — keep away from flame
Pseudomembranous colitis has been reported with antibiotic use, including topical erythromycin
Avoid concurrent use with topical clindamycin (antagonism) unless directed
Cumulative irritation may occur with other topical acne products (e.g., peeling agents)
Tell your provider if pregnant or breastfeeding before use

Tell your prescriber about all medications, supplements, and health conditions before starting erythromycin topical solution 2%.

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Frequently Asked Questions

What is erythromycin topical used for?

Erythromycin topical is a prescription antibiotic solution used to treat acne vulgaris. It reduces acne-causing bacteria on the skin and helps improve inflammatory breakouts such as papules and pustules.

Do I need a prescription for erythromycin topical solution?

Yes. Erythromycin topical solution 2% is a prescription-only medication in the U.S. A licensed provider must review your health information and approve treatment before it can be dispensed.

How does ordering and shipping work?

After you complete a brief health questionnaire, a licensed provider reviews your information. If appropriate, your prescription is filled and shipped from a licensed U.S. pharmacy directly to your address.

How do I apply erythromycin topical solution?

Wash and dry the affected skin, then apply a thin layer to the area twice daily, usually morning and evening. Avoid contact with the eyes, nose, and mouth, and wash your hands after applying.

How long does erythromycin topical take to work?

Many people begin to see improvement within a few weeks, but full results can take longer. Use it consistently as directed and follow up with your provider if acne does not improve.

Can I use erythromycin topical with other acne products?

Using it alongside other drying or peeling products (like benzoyl peroxide or retinoids) may increase irritation. Tell your provider about all skin products you use so they can guide your routine.