Medroxyprogesterone 2.5mg

Generic For: Provera

Medroxyprogesterone 2.5mg (brand name Provera) is a progestin tablet used to treat secondary amenorrhea and abnormal uterine bleeding caused by hormonal imbalance, and to reduce the risk of endometrial hyperplasia in postmenopausal women taking estrogen. After a licensed provider reviews your health information and issues a valid prescription, your order ships from a licensed U.S. pharmacy.

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Buy Medroxyprogesterone 2.5mg (Provera) Online

A progestin medication for secondary amenorrhea, abnormal uterine bleeding, and endometrial hyperplasia prevention

Medroxyprogesterone 2.5mg Quick Facts

Drug classProgestin (synthetic progesterone)
TreatsSecondary amenorrhea, abnormal uterine bleeding, endometrial hyperplasia prevention
FormTablet
Typical dosingTake as directed by primary physician by mouth.
Prescription requiredYes — prescription only

What Is Medroxyprogesterone 2.5mg?

Medroxyprogesterone is a synthetic form of the hormone progesterone, sold under the brand name Provera. It works by helping regulate the lining of the uterus (endometrium) when the body's natural hormone balance is disrupted. Doctors prescribe medroxyprogesterone tablets to restore menstrual periods that have stopped, to manage abnormal uterine bleeding, and to protect the uterine lining in postmenopausal women using estrogen therapy. It is available by prescription only and is taken by mouth as directed by your provider.

What Does Medroxyprogesterone 2.5mg Treat?

Secondary amenorrhea (absence of menstrual periods)
Abnormal uterine bleeding due to hormonal imbalance
Prevention of endometrial hyperplasia in postmenopausal women receiving estrogen
Support of regular menstrual cycles when prescribed by a provider

Medroxyprogesterone 2.5mg Dosage

Secondary amenorrhea: 5–10 mg by mouth once daily for 5–10 days.
Abnormal uterine bleeding: 5–10 mg by mouth once daily for 5–10 days, starting on day 16 or 21 of the cycle.
Endometrial hyperplasia prevention (with estrogen): 5–10 mg by mouth once daily for 12–14 consecutive days per month.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Medroxyprogesterone 2.5mg Side Effects

Common side effects

  • Breast tenderness
  • Headache
  • Nausea
  • Breakthrough bleeding or spotting
  • Changes in menstrual flow
  • Weight changes
  • Mood changes
  • Dizziness

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Blood clots (leg pain/swelling, chest pain, shortness of breath)
  • Sudden vision changes or loss of vision
  • Severe headache or migraine
  • Signs of stroke (weakness, slurred speech)
  • Jaundice (yellowing of skin or eyes)
  • Severe allergic reaction (rash, swelling, difficulty breathing)

Warnings & Interactions

Do not use if pregnant or if pregnancy is suspected
Contraindicated with a history of blood clots, stroke, or heart attack
Contraindicated with known or suspected breast cancer or undiagnosed vaginal bleeding
Do not use with liver impairment or liver disease
Combined estrogen-progestin therapy may increase risks of cardiovascular events and breast cancer (boxed warning)
Not for prevention of cardiovascular disease or dementia
Tell your provider about all medications, including CYP3A4 inducers such as rifampin or St. John's wort

Tell your prescriber about all medications, supplements, and health conditions before starting medroxyprogesterone 2.5mg.

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Frequently Asked Questions

What is medroxyprogesterone used for?

Medroxyprogesterone is a progestin used to treat secondary amenorrhea (missed periods) and abnormal uterine bleeding caused by hormonal imbalance. The 2.5mg strength is also used with estrogen in postmenopausal women to reduce the risk of endometrial hyperplasia.

Is medroxyprogesterone the same as Provera?

Yes. Provera is the brand name for medroxyprogesterone acetate tablets. Generic medroxyprogesterone contains the same active ingredient and works the same way.

Do I need a prescription for medroxyprogesterone?

Yes, medroxyprogesterone is a prescription-only medication in the U.S. A licensed provider must review your health history and confirm the medication is appropriate before it can be dispensed.

How does ordering and shipping work?

After you complete a brief health questionnaire, a licensed provider reviews your information. If a prescription is issued, your medication is filled and shipped from a licensed U.S. pharmacy directly to your address.

How long does it take medroxyprogesterone to work?

When used for missed periods or abnormal bleeding, withdrawal bleeding typically occurs within 3 to 7 days after finishing the prescribed course. Your provider will explain what to expect based on your treatment plan.

Can I take medroxyprogesterone if I'm pregnant?

No. Medroxyprogesterone should not be used during pregnancy or if pregnancy is suspected. Talk with your provider right away if you think you may be pregnant while taking this medication.

What should I avoid while taking medroxyprogesterone?

Avoid smoking, which raises the risk of blood clots, and tell your provider about all medications and supplements you take, including St. John's wort. Report any unusual bleeding, leg swelling, chest pain, or vision changes promptly.