Medroxyprogesterone 5mg

Generic For: Provera

Medroxyprogesterone (brand name Provera) is a prescription progestin tablet used to treat secondary amenorrhea and abnormal uterine bleeding due to hormonal imbalance, and to reduce the risk of endometrial hyperplasia in women taking estrogen. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.

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100-day supply · $0.45/tablet

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Price: $45.00

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Buy Medroxyprogesterone 5mg (Provera) Online

A progestin tablet for secondary amenorrhea, abnormal uterine bleeding, and endometrial protection during estrogen therapy

Medroxyprogesterone 5mg Quick Facts

Drug classProgestin (synthetic progesterone)
TreatsSecondary amenorrhea, abnormal uterine bleeding, endometrial hyperplasia prevention
FormTablet
Typical dosingTake as directed by primary physician by mouth.
Prescription requiredYes — prescription only

What Is Medroxyprogesterone 5mg?

Medroxyprogesterone is a synthetic form of the hormone progesterone, sold under the brand name Provera. It works by regulating the growth and shedding of the uterine lining. Doctors prescribe it to restore menstrual periods that have stopped (secondary amenorrhea), to manage abnormal uterine bleeding caused by hormonal imbalance, and to protect the uterine lining in women taking estrogen for menopause. It is available as a 5mg oral tablet and requires a prescription in the United States.

What Does Medroxyprogesterone 5mg Treat?

Secondary amenorrhea (absent menstrual periods)
Abnormal uterine bleeding due to hormonal imbalance
Prevention of endometrial hyperplasia in postmenopausal women taking estrogen
Induction of a withdrawal bleed to regulate the menstrual cycle

Medroxyprogesterone 5mg Dosage

Secondary amenorrhea: 5–10 mg by mouth once daily for 5–10 days.
Abnormal uterine bleeding: 5–10 mg by mouth once daily for 5–10 days, beginning on day 16 or 21 of the cycle.
Endometrial hyperplasia prevention: 5–10 mg by mouth once daily for 12–14 consecutive days per month, with estrogen.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Medroxyprogesterone 5mg Side Effects

Common side effects

  • Breast tenderness
  • Headache
  • Nausea
  • Bloating
  • Breakthrough bleeding or spotting
  • Changes in menstrual flow
  • Weight changes
  • Mood changes

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Blood clots (leg pain/swelling, chest pain, shortness of breath)
  • Stroke symptoms (sudden weakness, vision changes, severe headache)
  • Jaundice or signs of liver problems
  • Severe allergic reaction (rash, swelling, difficulty breathing)
  • Sudden partial or complete vision loss
  • New breast lumps

Warnings & Interactions

Do not use if pregnant or if pregnancy is suspected
Contraindicated with known or suspected breast cancer
Contraindicated with undiagnosed abnormal vaginal bleeding
Do not use with active or history of blood clots (DVT, PE, stroke)
Contraindicated with liver disease or impaired liver function
Boxed warning: estrogen plus progestin therapy may increase risk of heart disease, stroke, blood clots, and breast cancer
Tell your provider about all medications, including enzyme-inducing drugs that may reduce effectiveness

Tell your prescriber about all medications, supplements, and health conditions before starting medroxyprogesterone 5mg.

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Frequently Asked Questions

What is medroxyprogesterone used for?

Medroxyprogesterone is a progestin used to treat secondary amenorrhea (absent periods) and abnormal uterine bleeding caused by hormonal imbalance. It is also prescribed alongside estrogen to reduce the risk of endometrial hyperplasia in postmenopausal women.

Is medroxyprogesterone the same as Provera?

Yes. Provera is the brand name for medroxyprogesterone acetate tablets. The 5mg tablet contains the same active ingredient whether dispensed as brand or generic.

Do I need a prescription for medroxyprogesterone 5mg?

Yes, medroxyprogesterone is a prescription-only medication in the United States. A licensed healthcare provider must evaluate whether it is appropriate for you before it can be dispensed.

How does ordering and shipping work?

After you submit a valid prescription, a licensed provider or pharmacist reviews your order. Once approved, your medication ships from a licensed U.S. pharmacy directly to your address.

How long does it take medroxyprogesterone to work?

For secondary amenorrhea or abnormal bleeding, a withdrawal bleed typically occurs within 3–7 days after finishing a course of tablets. Your provider will advise what to expect based on your treatment plan.

Can I take medroxyprogesterone while pregnant?

No. Medroxyprogesterone should not be used during pregnancy or if pregnancy is suspected. Contact your provider right away if you think you may be pregnant while taking it.

What should I avoid while taking medroxyprogesterone?

Avoid smoking, which raises the risk of blood clots, and tell your provider about all medications you take, as some drugs can reduce medroxyprogesterone's effectiveness. Report any unusual bleeding, leg swelling, chest pain, or vision changes promptly.