Metronidazole 0.75% Topical Cream

Generic For: MetroCream

Metronidazole topical 0.75% cream (MetroCream) is a prescription antibiotic applied to the skin to treat the inflammatory papules and pustules of rosacea. After a licensed provider reviews your order, it ships directly to you from a licensed U.S. pharmacy.

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14-day supply · $0.56/gram

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Buy Metronidazole 0.75% Topical Cream (MetroCream) Online

A topical antibiotic cream for rosacea, including the inflammatory papules and pustules of rosacea

Metronidazole 0.75% Topical Cream Quick Facts

Drug classTopical nitroimidazole antibiotic
TreatsRosacea, inflammatory papules of rosacea, pustules of rosacea
FormCream
Typical dosingApply to affected area twice a day
Prescription requiredYes — prescription only

What Is Metronidazole 0.75% Topical Cream?

Metronidazole topical is an antibiotic cream applied directly to the skin. The 0.75% strength, sold under the brand name MetroCream, is FDA-approved to treat the inflammatory papules and pustules of rosacea in adults. It works locally on the skin and is thought to reduce inflammation associated with rosacea lesions. It is available by prescription only and is typically used as part of an ongoing rosacea management plan directed by your provider.

What Does Metronidazole 0.75% Topical Cream Treat?

Rosacea (papulopustular type)
Inflammatory papules of rosacea
Pustules (pimple-like bumps) of rosacea
Ongoing maintenance of rosacea lesions as directed by a provider

Metronidazole 0.75% Topical Cream Dosage

Apply a thin layer to affected area(s) twice daily, morning and evening.
Cleanse skin before applying; continue as directed by your prescriber.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Metronidazole 0.75% Topical Cream Side Effects

Common side effects

  • Skin redness at application site
  • Dryness
  • Stinging or burning
  • Itching
  • Skin irritation
  • Worsening of rosacea symptoms (temporary)
  • Watery eyes if applied near the eye area

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Severe skin irritation requiring discontinuation
  • Allergic reaction (rash, hives, swelling of face or throat)
  • Numbness or tingling in hands or feet (peripheral neuropathy)
  • Eye irritation from contact with the eyes

Warnings & Interactions

For external (topical) use only; avoid contact with eyes and mucous membranes
Do not use if allergic to metronidazole or other nitroimidazoles
Avoid or limit alcohol; oral metronidazole can cause disulfiram-like reactions and caution is advised
May interact with warfarin (blood thinners); tell your provider if you take anticoagulants
Use caution in patients with blood dyscrasias or a history of them
Tell your provider if pregnant or breastfeeding before use
Discontinue and contact your provider if severe irritation occurs

Tell your prescriber about all medications, supplements, and health conditions before starting metronidazole 0.75% topical cream.

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Frequently Asked Questions

What is metronidazole topical used for?

Metronidazole topical 0.75% cream is FDA-approved to treat the inflammatory papules and pustules of rosacea in adults. It is applied directly to affected skin and works locally to reduce rosacea lesions.

Do I need a prescription for metronidazole topical cream?

Yes. Metronidazole 0.75% cream is a prescription-only medication in the U.S. A licensed provider must review your health information and approve the prescription before it can be dispensed.

How do I apply metronidazole 0.75% cream?

Wash the affected area, then apply a thin layer twice daily, morning and evening, or as directed by your prescriber. Avoid getting the cream in your eyes or mouth.

How long does metronidazole topical take to work for rosacea?

Many people notice gradual improvement over several weeks of consistent use, though results vary. Continue using it as prescribed and follow up with your provider if symptoms do not improve.

Can I drink alcohol while using metronidazole topical?

Although skin absorption is low, oral metronidazole can cause unpleasant reactions with alcohol, so caution is advised. Ask your provider or pharmacist about alcohol use during treatment.

How does ordering and shipping work?

After you place your order, a licensed provider reviews your health information to confirm the medication is appropriate. Once approved, your prescription is filled and shipped from a licensed U.S. pharmacy.

What are the most common side effects of metronidazole topical?

Common side effects include mild redness, dryness, stinging, burning, or itching where the cream is applied. Contact your provider if irritation is severe or does not improve.